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Video: Quantitative Measurement of GLUT4 Translocation to the Plasma Membrane by Flow Cytometry
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Nick Kimball on Instagram: "How do you add volume? • Glycogen depletion → GLUT4 translocation (↑ insulin sensitivity, improved nutrient partitioning) • Mechanical + metabolic stress → local IGF-1 / MGF signaling (satellite cell activity, muscle remodeling) • Higher-rep volume supports hypertrophy + fat loss when calories and protein are adequate • Low-rep, low-volume training still matters (max strength, neural efficiency, fatigue control) No training style works in a vacuum. No calories → no gr
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Instagramstrong_fast_lean
High volume depletes more glycogen, and depleting glycogen results in more GLUT4 translocation, which results in better insulin sensitivity, which means better nutrient partitioning. So the nutrients you ingest go to your muscles instead of your fat. The reason I use finishers is because achieving high volume with heavy weight is very difficult. I enjoy the strength adaptations that come with training in the low rep range, but I also enjoy the metabolic advantages of higher volume training. That
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