The Sinclair Method has been confirmed to be effective in more than 90 clinical trials around the world and observed to be successful in approximately 80 percent of problem drinkers. It is considered the …

Dec 21, 2025 · The Sinclair Method is an increasingly popular option that takes a gentler approach to curbing drinking. It relies on medication to make drinking feel less pleasurable, reducing the urge to …

Jul 26, 2025 · What is The Sinclair Method (TSM)? The Sinclair Method (TSM) is an evidence-based approach for treating Alcohol Use Disorder (AUD) using pharmacotherapy to reduce dependence on …

Discover how The Sinclair Method works. Science-backed alcohol treatment using Naltrexone, proven to help you reduce drinking, control cravings and regain balance, all with private, trusted support across …

Mar 29, 2022 · In a nutshell, the Sinclair Method (TSM) is a medication-assisted, evidence-based form of treatment for alcohol use disorder (AUD). Via the use of the prescription drug naltrexone, TSM …

The use of naltrexone targeted for use before drinking is popularly cred-ited to John David Sinclair, PhD (1943–2015), whose animal research showed that alcohol’s reinforcing effect could be blocked by …

The Sinclair Method, a transformative approach to treating alcohol use disorder, employs a unique strategy that differs significantly from traditional treatments such as abstinence-based programs or …

Oct 27, 2023 · The Sinclair Method is a treatment approach for treating alcohol use disorder. Unlike pure abstinence, this strategy entails taking the opioid antagonist, naltrexone, before drinking. Naloxone …

The Sinclair method is a form of treatment for alcohol use disorder that focuses on reducing use rather than maintaining complete abstinence. This may be an option to consider if your loved one is …

With The Sinclair Method, alcohol use can be reduced over time. The method is used when patients want increased control over problematic drinking patterns.