Tuberculosis (TB) - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version.

This article’s purpose is to discuss the seven relative steps in active M. tuberculosis infection, tuberculosis pathophysiology, and disease transmission in the eventual context of clinical …

Tuberculosis (TB) (see the image below), a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious disease–related mortality worldwide.

Jun 30, 2025 · In this Review, we outline the physiological and metabolic features thought to underpin the survival, evasion and subversion strategies employed by M. tuberculosis as it drives a cycle of...

Apr 17, 2025 · TB disease occurs when tubercle bacilli overwhelm the immune system of someone with latent TB infection and multiply. If a person is infected with TB bacteria, and the immune system …

Active TB symptoms include: You won’t have symptoms if you have inactive TB. But you might have a positive TB test. Mycobacterium tuberculosis bacteria cause TB. The germs spread through the air …

Mar 12, 2025 · The microbiology, pathogenesis, and immunology of TB will be reviewed here. Other issues related to TB infection and disease are discussed separately (see related topics).

Apr 24, 2025 · Active TB disease happens when the immune system can't control an infection. Germs cause disease throughout the lungs or other parts of the body. Active TB disease may happen right …

Using rabbit models, Dr. Arthur Dannenberg described the pathology of tuberculosis in detail [2, 3]. There are five stages: onset, symbiosis, early stages of caseous necrosis, interplay of cell-mediated …

In this review, we summarize the pathogenesis of TB infection, therapeutic targets, and corresponding modulators, including first-line medications, current clinical trial drugs and molecules in preclinical …