Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3][4][5] It is usually diagnosed in infancy or early …

What is spinal muscular atrophy? Spinal muscular atrophy (SMA) represents a group of genetic (inherited) neuromuscular disorders that cause certain muscles to become weak and waste away …

Jul 30, 2024 · Insufficient levels of SMN protein leads to loss of motor neurons in the spinal cord and causes weakness and wasting of the skeletal muscles. The most common form of SMA is caused by …

Spinal muscular atrophy (SMA) is a disorder affecting the motor neurons—nerve cells that control voluntary muscle movement. These cells are located in the spinal cord.

Spinal muscular atrophy is a genetic disorder characterized by weakness and wasting (atrophy) in muscles used for movement (skeletal muscles). It is caused by a loss of specialized nerve cells, …

Aug 11, 2025 · Spinal muscular atrophy (SMA) is a genetic neuromuscular disease affecting specialized nerve cells that control voluntary muscle movement, according to the Muscular Dystrophy Association...

Find out about spinal muscular atrophy (SMA) including the symptoms, types, causes, how it's diagnosed and the treatment and support available.

Apr 7, 2023 · Spinal muscular atrophy (SMA) is a rare genetic syndrome usually caused by changes to the SMN1 gene. It weakens your voluntary muscles. SMA mostly impacts your lower body and …

Aug 22, 2025 · SMA symptoms, as well as their severity and age of onset, vary by SMA type. The five main types of SMA — 0, 1, 2, 3, and 4 — are classified based on the age of symptom onset and the …

Aug 11, 2025 · New therapies and early screening are changing the outlook for spinal muscular atrophy, experts say.