Depending on one’s perspective, the anti-inflammatory colchicine is either an unsung and underprescribed drug for patients with cardiovascular disease, or it’s an agent with limited clinical benefit ...

While conducting the CLEAR SYNERGY (OASIS 9) trial, lead author Sanjit Jolly, MD continued to treat some of his patients post–myocardial infarction (MI), including his late father, with colchicine.

NEW YORK — New insights into colchicine's disruption of the pathway that contributes to arterial inflammation and new clinical studies of the drug could pave the way toward greater use of the ...

BASEL, Switzerland—Low-dose colchicine doesn’t significantly reduce MACE in patients who have had a nonsevere ischemic stroke or high-risk TIA, according to the results of the CONVINCE trial. Through ...

Please provide your email address to receive an email when new articles are posted on . Patients taking colchicine had a weighted hazard ratio of 0.82 (95% CI, 0.69-0.94) for cardiovascular events.

Dear Dr. Roach: I’m a 78-year-old man with a stent and a blockage in one of the arteries to my heart. I am on a low-fat diet and take ramipril for cholesterol. My levels are very good (total ...

WASHINGTON, DC – OCTOBER 29, 2024 – The largest trial to examine the impact of colchicine in acute myocardial infarction (MI) found that both acute and long-term colchicine use did not reduce ...

Colchicine use is associated with a modest reduction in the long-term risk for total joint arthroplasty (TJA) among individuals with gout, according to study findings published in Arthritis & ...

In the international CONVINCE trial, presented today (15 May 2024) at the European Stroke Organisation Conference (ESOC) 2024, anti-inflammatory treatment with long-term colchicine did not reduce ...

Colchicine is a potent anti‐inflammatory agent widely employed in the treatment of gout and related conditions. However, its narrow therapeutic window renders it a considerable toxicological risk, ...

(Boston)—Gout is the most common form of inflammatory arthritis, with worldwide prevalence of approximately four%. The accumulation of monosodium urate crystals in gout leads to the clinical ...