Sodium iodide symporter (NIS)-based radionuclide therapy provides an effective means of treating malignant tumors. However, it is sometimes inadequate and its effects on radio-resistant tumors are ...
Besides its canonical role in stabilizing telomeres, telomerase reverse transcriptase (TERT) may promote tumorigenesis through extra-telomeric functions. The possible therapeutic effects of BIBR1532 ...
A large, multicenter, retrospective study to identify a cutoff of MGMT methylation status by quantitative pyrosequencing approach in patients (PTS) with glioblastoma (GBM).
New research shows a transcriptase that helps time cell death varies in expression, and is unusually localized, in cancer cells. The transcriptase, Telomerase Reverse Transcriptase (TERT), is ...
A small-molecule compound named TAC has been identified that reawakens the catalytic subunit of telomerase (TERT) in somatic cells and, in doing so, stalls multiple hallmarks of natural aging without ...
Telomerase reverse transcriptase (TERT), an enzyme associated with nearly all malignant human cancers, is even more diverse and unconventional than previously realized, new CU Boulder research finds.
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