Neuronal TDP-43 pathology marks most cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but how does a single protein fit with such a wide range of symptoms? Researchers ...
The TDP-43 RNA-binding protein is found in abnormal cytoplasmic inclusions in affected motor neurons in almost all ALS cases, and mutations in the TDP-43 gene (TARDBP) cause a rare form of familial ...
AMSTERDAM & BOSTON, December 03, 2025--(BUSINESS WIRE)--VectorY Therapeutics, a leader in vectorized antibody therapies for neurodegenerative diseases, announced today that the U.S. Food and Drug ...
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