Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications ...

A biomimetic synapse built from water droplets and biological ion channels achieves synaptic plasticity and performs machine learning tasks.

A new study published in Cell is reshaping our understanding of the fundamental building blocks of the brain, the proteins that are present at synapses. Titled "The proteomic landscape of synaptic ...

An interdisciplinary team of scientists at the Max Planck Florida Institute for Neuroscience have developed a novel approach to measure the activity and strength of individual synapses that drive a ...

Brain cells called astrocytes play a key role in helping neurons develop and function properly, but there's still a lot scientists don't understand about how astrocytes perform these important jobs.

The death of synapses, and the neurons that need them, marks the inevitable endgame of Alzheimer’s disease. Despite this eventual synaptic mayhem, a new work, led by Thomas Südhof and Marius Wernig at ...

Family with sequence similarity 19 member A5 (FAM19A5) is a secretory protein highly expressed in the brain that regulates synapse dynamics through its interaction with leucine-rich repeat-containing ...