What is MR: MR uses genetic variants as tools to infer causality between exposures and outcomes, reducing confounding common in observational studies. Why it matters: It offers a way to test causal ...

This study explores the relationship between gallstones, cholecystectomy, and cancer risk through both observational and Mendelian randomization (MR) methods. The research aims to clarify the ...

As climate change accelerates and global temperatures continue to rise, a new randomized clinical trial provides compelling ...

Evidence-based practices for reducing opioid-related overdose deaths include overdose education and naloxone distribution, the use of medications for the treatment of opioid use disorder, and ...

Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits In the article that accompanies this ...

Pegozafermin is a long-acting glycopegylated (pegylated with the use of site-specific glycosyltransferases) fibroblast growth factor 21 (FGF21) analogue in development for the treatment of ...

Adam Hayes, Ph.D., CFA, is a financial writer with 15+ years Wall Street experience as a derivatives trader. Besides his extensive derivative trading expertise, Adam is an expert in economics and ...