Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

The brain is an extremely heterogeneous tissue. Within one small piece, there are neurons transmitting information, oligodendrocytes and astrocytes acting as support cells and microglia functioning as ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Inflammatory bowel disease (IBD) is an umbrella term for Crohn's disease and ulcerative colitis, which both involve chronic inflammation ... | Cell And Molecular Biology ...

Breakthrough research details how distinct tissue niches and cell communication contribute to chronic active lesions in MS. Study: Cell type mapping reveals tissue niches and interactions in ...

A whole developing wheat spike, 1mm scale. The blue represents fluorescent staining for DNA withing the nuclei. There are different coloured spots showing gene expression detected using the probes in ...