Medically reviewed by Oluseun Olufade, MD Key Takeaways Quadriparesis means muscle weakness in both arms and legs. Infections ...

Since she was born 20 years ago, Sylva Eugenie Davis of Kansas City has not been able to use her arms or legs. The nerve tracts in the neck region of her spinal cord were injured at birth, causing ...

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Spastic limb paralysis due to injury to a cerebral hemisphere can cause long-term disability. We investigated the effect of grafting the contralateral C7 nerve from the nonparalyzed side to the ...

Hereditary spastic paraplegia (HSP) comprises a heterogeneous group of neurodegenerative disorders that are mainly characterised by progressive spasticity and weakness of the lower limbs. Recent ...

A joint study conducted by the University of Bonn and the DZNE has confirmed early-stage brain inflammation in mice. Patients with spastic paraplegia type 15 develop movement disorders during ...

A disease-causing gene in hereditary spastic paraplegia bolsters the theory of altered lipid processing as a shared cause in motor neuron diseases. Genetic and cellular studies, led by Andrew Crosby ...

Spastic cerebral palsy is a disorder that involves muscle stiffness. Symptoms and signs may include difficulty walking, trouble manipulating objects, and vision, hearing, or speech challenges.