The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.
What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...
circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor ...
We identified twelve novel saliva and serum miRNAs and a panel of unique miRNA and mRNA signatures, significantly differentially expressed in saliva and serum of OSCC patients versus HC ...
SickKids researchers discovered that a long non-coding RNA, CISTR-ACT, directly regulates cell size. Using gene-editing tools, they showed that increasing CISTR-ACT shrinks cells, while removing it ...
What are Micro-RNAs (miRNAs)? Micro-RNAs (miRNAs) are a class of small, non-coding RNA molecules that play a crucial role in regulating gene expression at the post-transcriptional level. These tiny ...