Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

Bacterial ribosomes are central to protein synthesis, and their regulation is vital for adaptation to environmental stresses. Under conditions such as nutrient deprivation, cold shock or hypoxia, ...

A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its ...

Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the ...

Ribosomes are molecular machines that translate messenger RNA (mRNA), which is transcribed from DNA, into proteins. Scientists have now learned more about ribosomes in nature, and their function. This ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

Aging leads to a decline in cellular fitness and loss of optimal protein function. The mechanisms underlying how aging causes proteins to aggregate have not been fully understood. Using models of ...

Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...

A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its ...