Structure-based RNA could lead to treatment for neuromuscular disorders

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...
C&EN

Machine-learning approach predicts RNA structures

A new machine-learning approach assesses the accuracy of structural models of RNA molecules. From a training set of known RNA structures, the algorithm learns the characteristic features of RNA, such ...
News Medical

Deep learning revolutionizes RNA 3D structure prediction with RhoFold+

In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep ...
Carnegie Mellon University

Breakthrough in RNA Research Could Lead to Treatment for Neuromuscular Disorders

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for myotonic dystrophy type 1 (DM1), the most common adult-onset form of ...
News Medical

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

After a gene is transcribed into RNA, modifications can occur to the subunits or "bases" that make up the RNA molecule, which can affect its structure and function. The study of these changes is known ...
Psychology Today

Stanford’s State-of-the-Art AI for Predicting RNA Structures

Predicting RNA (ribonucleic acid) structures may help accelerate the discovery and development of new drugs to treat diseases and disorders. A new Stanford study published in Science uses artificial ...
FierceBiotech

New type of RNA degrader lowers COVID-19 viral load in mice, opening path to new drug class

While targeted protein and RNA degradation are hot areas for R&D, the drugs developed so far come with limitations. Now, a new class with broader applications may not be far off. In a study published ...
mskcc.org

With Cryo-EM, SKI Scientists Determine Structure of Key Factor in RNA Quality Control

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved ...
eLife

Dilated cardiomyopathy-associated RNA-binding motif protein 20 regulates long pre-mRNAs in neurons

An alternative splicing regulator previously implicated in calcium signaling in the heart ensures cell-type-specific mRNA processing of long neuronal mRNAs in the mouse brain.