It's been generally assumed that RNA molecules and proteins have only limited or transient interactions in cells, like when proteins that can bind to RNA molecules influence the translation of genes, ...

A new study on fatty acid acylation, or attachment, patterns onto proteins in Caenorhabditis elegans, a type of roundworm, provides a foundation for future discoveries around protein function and its ...

Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.

Eight histones assemble into so-called nucleosomes, around which DNA is wrapped and thereby compacted. Chemical modification of these proteins while they are being synthesized is crucial for proper ...

A research team led by Professor Seung Soo Oh and Dr. Hyesung Jo from the Department of Materials Science and Engineering at POSTECH (Pohang University of Science and Technology) has developed an ...

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

N-terminal acetylation represents one of the most ubiquitous protein modifications in eukaryotic cells, with significant implications for protein stability, folding, and interactions. This covalent ...

Boston College researchers have used a mild charge of electricity to precisely modify proteins—a new and inexpensive tool that can be used to develop novel biotherapeutics and protein-based research ...

Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the ...