One of the main goals of proteomics is to unravel the many modifications important for biological activity. Post-translational modifications (PTMs) extend the range of protein function by attaching it ...

Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.

The focus of vertebrate studies has mainly been on canonical phosphorylation, but research indicates that phosphorylation of other non-canonical amino acids also regulates integral aspects of cell ...

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known ...

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. Additionally, about one-fourth of the world's population carries Mycobacterium ...

A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological ...

Objectives Smoking is recognised as one of the strongest environmental risk factors for the development of rheumatoid ...

New research reveals that subtle chemical changes to proteins after synthesis play a critical role in determining ...

Protein changes matter: Scripps Research showed that post-translational modifications can make proteins more or less responsive to drug-like molecules, affecting treatment success. Genetics meets ...