Researchers have deciphered the long-sought atomic structure of PRC2, an enzyme complex that plays a key role in the development of several types of cancer, in particular blood cancer. Researchers at ...
A new study published in the journal Nature Medicine by NYU Cancer Institute researchers, shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 (PRC2) ...
Forty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins called PRC2 has become a key target for new cancer-fighting drugs, due to its tendency—when mutated ...
Lab scientists use cryo-electron microscopy to gain a deeper understanding of the structure of a regulatory complex. Their research could open up new possibilities for cancer therapies. All the ...
The approach will allow researchers to understand the role individual genes play in normal cell growth and development, in aging, and in such diseases as cancer, said Shiri Levy, a postdoctoral fellow ...
The approach will allow researchers to understand the role individual genes play in normal cell growth and development, in aging, and in such diseases as cancer, said Shiri Levy, a postdoctoral fellow ...