Researchers have deciphered the long-sought atomic structure of PRC2, an enzyme complex that plays a key role in the development of several types of cancer, in particular blood cancer. Researchers at ...
A new study published in the journal Nature Medicine by NYU Cancer Institute researchers, shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 (PRC2) ...
Forty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins called PRC2 has become a key target for new cancer-fighting drugs, due to its tendency—when mutated ...
Lab scientists use cryo-electron microscopy to gain a deeper understanding of the structure of a regulatory complex. Their research could open up new possibilities for cancer therapies. All the ...
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