Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease ...

Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research. Mice don't get ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Researchers have identified a protein that links brain immune activity, metabolism, and amyloid clearance, suggesting a new way to enhance current Alzheimer’s treatments. Alzheimer’s disease can look ...

One of those genes encodes the enzyme DHDDS, part of the pathway that glycosylates proteins in higher cells. Retinitis pigmentosa from DHDDS mutations is called RP59. This is a recessive genetic ...

Researchers at Oregon State University have developed and tested in a mouse model a new type of nanoparticle that enables the removal of melanoma tumors with a low-power laser. After the systemically ...

The Tonks lab studied PTP1B inhibition in a mouse model of Alzheimer’s disease. When PTP1B was deleted, as shown in the bottom row, the brain’s immune cells (green) were better at engulfing harmful ...