Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and ...

A new study reveals that nerve cells receive periodic infusions of mitochondria from neighboring cells — and this may point ...

Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...

You might know them as the “powerhouses of the cell,” but that’s selling mitochondria short—these microscopic MVPs play a role in almost everything that makes you healthy. With the right lifestyle ...

Longevity science has spent decades chasing single molecules that might slow aging, but most candidates have delivered modest, inconsistent results. A new line of research is now pointing to a ...

The grant will help advance treatments for the life-threatening lung condition acute respiratory distress syndrome.