Shifting brain glucose levels act as a metabolic switch that directs OPC proliferation and myelin formation, revealing a mechanism with developmental and clinical implications.

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers. Published online in Science on Oct. 30, the study shows that ...

Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of infection, these so-called Tregs restrain the immune system to ensure it ...

Schematic model showing how memory is consolidated in the prefrontal cortex and how circuitry through the amygdala shifts as hippocampal engram cells become silent and cortical engrams become active.

New insight into the process that converts experiences into stable long-term memories has been uncovered by neurobiologists from the University of California, Irvine and the University of Queensland.

The freshwater pond snail Lymnaea stagnalis has emerged as an invaluable invertebrate model for the study of memory formation and central nervous system (CNS) function. Its relatively simple yet ...

Every flu season, injectable vaccines prime the immune system to produce antibodies that circulate through the bloodstream.

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...