One of the most enduring goals in regenerative medicine is deceptively simple: replace a person's damaged or dying cells with ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Phenotypic 3D cell models incorporate tissue architectures and extracellular matrices to recapitulate the complexity of the ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions ...

Over the last 15 years, I have witnessed how cell and gene therapy (CGT) has evolved in many ways, spanning from research and development to manufacturing. Breakthroughs such as CAR-T and gene therapy ...

MIT scientists have developed a new 3D human brain tissue model that could change how researchers study neurological diseases. The platform, called Multicellular Integrated Brains or miBrains, ...

Single-cell sequencing reveals cellular heterogeneity within models, while advanced imaging captures dynamic processes in living organoids. These tools, combined with rigorous validity assessment, ...

Creating human structures in a lab is always difficult, but when successful, it can open up a lot of possibilities. Recently, researchers have been working on using 3D embryo structures called ...

Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...