As we get older, chemical marks on our DNA slowly shift. Now, a study reveals this 'drift' in gut stem cells is fueled by ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic disease. Researchers have now traced a key part of that shift to specific ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

EPFL scientists have shown that a gene linked to a rare childhood disease is essential for regenerating intestinal stem cells after injury. Our intestines are constantly renewing themselves, replacing ...

The study, “A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts,” was published in Immunity. The team, led by Carlene L. Zindl, Ph.D., found that IL-22 ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

During drug development, researchers need to perform adequate nonclinical testing to ensure a drug’s safety and efficacy before starting clinical trials. An important aspect they must evaluate is a ...

Our intestine plays a vital role in absorbing nutrients and provides a protective barrier within the digestive tract. As a consequence of these functions, the epithelial cells lining the intestine are ...