Integer programming and combinatorial optimization form the backbone of many decision-making and resource allocation problems across diverse fields, from logistics and telecommunications to finance ...

The objective of the 3D-SCALO problem is to assign the given components to optimal mounting surfaces and position them at the best locations, while satisfying the requirements for (1) heat dissipation ...

Design of experiment plays a crucial role in the optimization process of formulation development. The process, equipment, and technology for developing and manufacturing oral solid-dosage forms are ...

Drug development often progresses from one phase to the next without considering long-term feasibility, such as scalability, cost-effectiveness, and market access. Sustainable success is assured by ...

QbD principles and strategic thinking can reduce the time required to optimize formulation. To help pharmaceutical and biotech companies improve their operations, FDA has been promoting the use of ...