The complement system, a proteolytic cascade within innate immunity, is tightly regulated during healthy gestation to support implantation, placental development and parturition while preventing ...

The complement system in teleost fish constitutes a cornerstone of innate defence, integrating classical, lectin and alternative activation routes to eliminate pathogens and shape inflammatory ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

1 Department of Internal Medicine, Division of Rheumatology, University of New Mexico, Albuquerque, NM 2 Biomedical Research Institute of New Mexico, Albuquerque, NM 3 Department of Molecular Genetics ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...