An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches. For people with tooth decay, drinking a cold beverage can be agony.

Odontoblasts, the cells that form a tooth's dentin, have a newly discovered function: Sensing cold, which can trigger pain in teeth; but scientists have also found a way to block the pathway to ...

Tooth sensitivity doesn't always mean you have cavities or decay. Although cavities are one of the causes of sensitive teeth ...

There’s a special type of pain when something that is just too cold hits your teeth. This pain is so visceral, medical textbooks written throughout human history have recounted tales of a “tooth worm, ...

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp ...

The UK recorded its coldest autumn so far when the temperatures fell as low as -12.6C in Scotland. This was the lowest recorded in November from the last 15 years. The mercury also fell to -7.6C in ...

For people with tooth decay, drinking a cold beverage can be agony. "It's a unique kind of pain," says David Clapham, vice president and chief scientific officer of the Howard Hughes Medical Institute ...