Macrophages are highly variable, and their ontogeny and functions depend on the particular organ in which they reside and on any ongoing disease processes. Lung macrophages are critically important to ...

Pulmonary alveolar proteinosis is a rare disorder in which lipoproteinaceous material accumulates within alveoli. 1 The clinical course of the disease is variable, ranging from respiratory failure to ...

Children with sickle cell disease (SCD) often have obstructive lung function abnormalities which could be due to asthma or increased pulmonary blood volume; it is important to determine the underlying ...

Types A and B Niemann-Pick disease (NPD) are lipid storage diseases caused by the deficient activity of the lysosomal enzyme, acid sphingomyelinase (ASM). Type B NPD is associated with progressive ...