Hot-melt extrusion (HME) has emerged as a game-changer in modern drug development—a solvent-free approach that transforms difficult compounds into effective medicines. This guide breaks down the ...

New formulations of currently available chemotherapy agents have the potential to reduce toxicity and/or increase efficacy. Paclitaxel is a standard chemotherapy agent for NSCLC and uses ...

To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

Scientists have successfully tested the use of machine learning models to guide the design of long-acting injectable drug formulations. The potential for machine learning algorithms to accelerate drug ...

Intrepid Labs’ Valiant platform uses AI and robotics to cut drug formulation timelines from months to days Over $11M USD total raised to-date; latest round led by AVANT BIO TORONTO--(BUSINESS ...

Non-invasive delivery systems, like needle-free nasal sprays, improve patient adherence by addressing psychological barriers and offering logistical advantages such as extended shelf life and ...

Expertise in CMC (chemistry, manufacturing, and control) ensures the appropriate manufacture of a pharmaceutical or biologic by coordinating material characterization, formulation development, and ...

Early on, the drug substance (DS) manufacturer will provide a wealth of preliminary characterization data. And if the drug is active in early nonclinical and preclinical testing, a larger quantity of ...

National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers has the following research output in the current window (1 October 2024 - 30 September 2025) of the Nature Index.

A group of researchers supported by FAPESP has developed a new formulation for the only drug available on the market to treat helminths, as worms such as schistosomes and tapeworms are known.