Rare disease clinical trials are smaller and often use surrogate endpoints, reducing costs but posing unique operational ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative ...

During development of the digestive system, a complex network of nerves forms around it, creating a "second brain" - the enteric nervous system (ENS) - which controls the movement of food and waste ...

Researchers have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that ...

A multimodal sleep foundation model based on polysomnography data can predict the risk for multiple conditions, including dementia.