DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

Every researcher knows the frustration: your groundbreaking experiment is on hold because the DNA sequence you need is "unmanufacturable". Or worse, after weeks of waiting, the oligos arrive with ...

AI can now create genome viruses in laboratories and redesign toxins to evade controls, raising biosafety alert and rise of ...

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

Demand for synthetic DNA is growing across multiple industries including cell and gene therapy development and biomanufacturing. Coupled with that growth is a need for genetic constructs that can, in ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...