Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Gene and cell therapy is moving fast – and in a clear direction. Programs are pushing toward more complex payloads, virus-free engineering, and manufacturing models that can scale from early research ...

Maize serves as a vital model species for advancing our understanding of plant biology, yet many mysteries remain about the ...

New research shows hydroxyurea reshapes DNA replication in cancer cells, revealing stress responses that may help design ...

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...

In a landmark simulation, scientists have recreated the full cell cycle of a living cell in four dimensions — three dimensions plus time. Using a highly detailed digital model of a minimal synthetic ...