Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine. Normally, creating better ...

It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...

Using directed evolution, researchers have developed an enzyme that catalyses the formation of biaryl bonds (Nature 2022, DOI: 10.1038/s41586-021-04365-7). This new enzyme makes carbon-carbon bonds ...

A new catalyst strategy developed at Institute of Science Tokyo uses BaSi2 as a support for nickel and cobalt to decompose ...

Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by ...