In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

Rare genetic variants in noncoding regions of the human genome can cause severe rare disease 1,2, but their role in common, complex traits is still largely unknown. Array-based imputation, genome-wide ...

The advent of high-throughput sequencing uncovered that our genome is pervasively transcribed into RNAs that are seemingly not translated into proteins. It was also found that non-coding RNA ...

Late in 2025, we covered the development of an AI system called Evo that was trained on massive numbers of bacterial genomes. So many that, when prompted with sequences from a cluster of related genes ...