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Tightening the focus of subcellular snapshots: Combined approach yields better cell slices for cryoET imaging
Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), shoots electrons through a frozen sample. The images formed by the electrons ...
Both images show individual red blood cells. The one on the right, produced by STED, more clearly shows the Piezo1 proteins (in green), which are a mechanical calcium channel and play a crucial role ...
A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...
Scientists at Feinberg are reshaping scientific understanding of the cell's tiniest components—structures once thought to be static, now revealed to be dynamic engines of cellular life. As they probe ...
In a study published in Cell Reports, biomedical scientist Xuecai Ge at the University of California, Riverside and her team ...
Scientists have attempted to map the human cell since the first microscope was invented more than 400 years ago. But many components of the cell still remain uncharted. "We know each of the proteins ...
Researchers at EPFL have created CenSpark, a fluorescent probe that selectively labels centrioles and cilia in living cells across species. The tool enables unprecedented live imaging without genetic ...
Northwestern Medicine scientists have uncovered how a specific type of cell in the inner ear plays a commanding role in shaping the cellular landscape of the organ responsible for hearing, according ...
Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...
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