A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

Cancer cells rewire their metabolism to support rapid proliferation, survival under stress and metastatic spread. This reprogramming encompasses a shift from mitochondrial oxidative phosphorylation to ...

Thyroid cancer cells undergo profound metabolic reprogramming to support rapid proliferation, survival under stress and metastatic spread. A hallmark of this reprogramming is the shift from ...

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...

BPM31510 is a first-in-class therapeutic targeting tumor metabolism to re-program mitochondrial microenvironment in Warburg-avid tumorsBoth ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer ...

A recent study has demonstrated the power of metabolic engineering in enhancing the antitumor activity of chimeric antigen receptor (CAR) macrophages (CAR-Ms) in solid tumors. By overexpressing the ...

A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change ...

GLP-1 drugs commonly used for weight loss and diabetes decreased the risk of cancer spreading in patients with several ...

Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting engineered particles can influence immune metabolism in ways that may ...

In tumors of active patients: Genes tied to cancer progression (angiogenesis, epithelial-mesenchymal transition) were less active. Genes involved in energy production (oxidative phosphorylation) were ...