Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism.

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice. Their work establishes a next-generation gene-editing tool that enhances genetic ...

Growing focus on gene-based therapies, advances in editing tools, and increasing research investments are accelerating the adoption of genome editing technologies across life sciences and agriculture.

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...