“If we want to address BBB dysfunction, we have to have a good human BBB model,” said Ziyuan Guo, a neurobiologist and stem cell scientist at Cincinnati Children's Hospital Medical Center. “The whole ...
Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that ...
A team of scientists at Texas Tech University Health Sciences Center (TTUHSC) has published new evidence suggesting that the brain's protective shield - known as the blood-brain barrier (BBB) - ...
According to Mr. Lee Ming-Juan, Vice General Manager of Shine Out Bio Technology, preclinical studies using <ALPHA>DAT-EVs loaded with curcumin have demonstrated promising therapeutic effects in both ...
- CANDID-CNS TM achieves an 83% success rate for predicting small molecule brain penetration and distribution versus a 64% success rate for the industry standard CNS-MPO score - Only ~2% of small ...
New nanomaterial passes the blood-brain barrier to reduce damaging inflammation after the most common form of stroke. When ...
The blood-brain barrier protects the central nervous system by tightly regulating what crosses between the two compartments. Neurons are vulnerable if the barrier suffers damage or weakens with age, ...
A TTUHSC research team published new evidence suggesting that the blood-brain barrier (BBB) remains largely intact in a commonly used mouse model of Alzheimer’s disease. Ehsan Nozohouri (seated), a ...
Micro- and nanoplastics are increasingly detected in human tissues, including the brain, and experimental evidence suggests ...
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