Cancer biomarkers span a broad biological spectrum, including proteins, metabolites, and nucleic acids detectable in samples such as tissue biopsies and blood. 1 At the beginning of a biomarker ...

However, regardless of which trial is conducted, the overfitting of data might be a substantial issue, meaning that the number of parameters in a model is too great relative to the number of samples, ...

In a recent editorial published in Current Pharmaceutical Analysis (Volume 18, Issue 6, 2022), researchers Dr. Behrouz Seyfinejad and Dr. Abolghasem Jouyban highlight the importance of method ...

Faculty in the Medical Devices and Diagnostics Hub develop statistical methods for the design, evaluation, and validation of diagnostic tools and medical devices. Their work includes biomarker ...

Background: The Prognostic Lung Fibrosis Consortium (PROLIFIC) was formed to develop well-qualified assays suitable for use as prognostic biomarkers within the context of clinical trials for Idiopathic ...

A multimodal artificial intelligence (MMAI)–derived predictive biomarker was trained for long-term (LT) versus short-term (ST) ADT using pretreatment digital prostate biopsy images and clinical data ...

We identify six causal molecular biomarkers (e.g., CNPY4, ENTPD6, HLA-A) and eight clinical biomarkers (e.g., serum total protein) for MASLD across various independent cohorts. Serum total protein ...

Study links exosomal microRNA to ventricular remodelling in heart failure. Discover how this biomarker could inform future ...