A Seven-fold Path for Defining Quality and Acceptable Performance Many articles have been written about the state of biomarker identification and validation using gene expression and proteomics. Many ...

Cancer biomarkers span a broad biological spectrum, including proteins, metabolites, and nucleic acids detectable in samples such as tissue biopsies and blood. 1 At the beginning of a biomarker ...

90% of breast cancer mortality is caused by distant metastasis, a process that involves both dissemination of cancer cells to distant sites as well as their proliferation after arrival. However, ...

Traditional approaches for detecting Alzheimer’s disease (AD) that rely on examining the brain for amyloid plaques have limitations in accuracy and early detection. Although the industry has ...

Protein biomarkers increasingly play a vital role in advancing health research, driving drug development, and improving clinical outcomes. The close connection between protein biomarkers and human ...

A key step towards reducing the burden of central nervous system (CNS) disorders is the identification of disease-specific biomarkers that can help predict, monitor, and guide treatment development.

Background: The Prognostic Lung Fibrosis Consortium (PROLIFIC) was formed to develop well-qualified assays suitable for use as prognostic biomarkers within the context of clinical trials for Idiopathic ...

Biomarkers—the biological indicators that can help serve as early warning signs for our health—have played an important role in science and are the key to personalized medicine. In the 20 years since ...