Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the range of conditions that can be identified at birth. Next-generation ...

Regulator of G-protein signaling (RGS) proteins modulate GPCR signaling, making them potential therapeutic targets for several conditions, including cardiovascular disease and diabetes. However, ...

In drug development projects, evaluating drug-target residence times can enhance drug efficacy, widen the therapeutic window, and reduce the likelihood of prematurely advancing candidate compounds ...

It achieves AI-driven generative design of the first permeable macrocyclic peptide with more than two polar or ionizable fragments. -- Surrogate assays are a breakthrough for AI model training. 1910 ...

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement. Could you start by explaining the significance of understanding cellular ...

We spoke with Scott Jones, PhD, SVP & CSO at BioBridge Global (BBG) to understand the challenges of product-specific potency ...

Scientists routinely consider the quality of experimental factors such as samples, reagents, and laboratory equipment when optimizing assay performance, however laboratory consumables are one category ...

Professor of Chemical and Biological Engineering, Biomedical Engineering, and Public Health, Colorado State University A vast number of chemicals are registered for production and use around the world ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...