Objective: To evaluate the bioequivalence of two enteric-coated formulations of omeprazole, Losec ® (reference) and Omepradex ® (test). It is hypothesised that formulation differences may be ...

PE: Can you elaborate on the key design elements of the AD04 study and how they contributed to achieving positive topline results? Claiborne: The purpose of the study was to evaluate the relative ...

Absorption, distribution, metabolism, and excretion (ADME) are four main processes that demonstrate how a drug behaves after being administered. Therefore, ADME is key in defining a compound’s ...

Sequences of topotecan and cisplatin: phase I, pharmacologic, and in vitro studies to examine sequence dependence. Twelve patients with refractory solid tumors were enrolled onto this three-period ...