Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer ...

Three decades after discoveries linking mutations in the BRCA1 gene to breast and ovarian cancer susceptibility, research led by Mays Cancer Center at The University of Texas Health Science Center at ...

In women who have both breast cancer and the BRCA1 mutation, having surgery to remove the ovaries can significantly lower their risk of dying from the disease, suggests a new study published in the ...

In this study, researchers aimed to determine whether younger BRCA1/2 carriers who undergo oophorectomy can receive menopausal hormone therapy without increasing their risk of breast cancer.

The current testing rate for BRCA 1/2 mutations is currently 68% in HER2-negative early breast cancer, but eligible patients could receive better care if tested. The current rate of BRCA1/2 testing ...

The full name of the BRCA1 gene is “breast cancer 1, early onset,” and it codes for a tumor suppressor protein. Tumor suppressor proteins help repair DNA that has become damaged in order to ensure the ...

When it was discovered by researchers in 1994, the BRCA1 gene was hailed as a landmark achievement not just in breast cancer prevention but in medicine in general. Its discovery led to the development ...