Combining statistical modeling with flow cytometry enables reliable, high-throughput quantification of division asymmetry in live cells, revealing how partitioning noise may shape tumor cell ...

In our February issue, Steven Reiner describes how lymphocytes make use of a highly unusual type of division to create two different kinds of cells: effector and memory. Here, you can see this ...

How does the body produce the diversity in T-cell fates that are essential for immunity? The symmetric division model predicts that the fate of each naïve T-cell is determined by the cytokines the ...

T cell division is critical to understand because of its role in the immune response. There is a myriad of T cell subcategories with different responsibilities. A few subcategories include cytotoxic T ...

It's long been assumed that when a parent cell divides into two daughter cells, the parent assumes a spherical shape, which then splits into two cells that have roughly the same, round size. But a new ...

The polarization of the scaffold-signaling hubs at cell poles constitutes the basis of ACD. However, the biomolecular basis and regulatory mechanism of the polar signaling complexes has been largely ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent ...

If you took high school biology, you probably learned about cell division: a crucial process in all life forms officially called mitosis. For over one hundred years, students have learned that during ...

Until now, cells dividing by mitosis were thought to grow round and then split into two identical, spherical daughter cells. New research has found that some cells are isomorphic, meaning they retain ...