In the cerebral cortex, extrinsic and intrinsic excitatory glutamatergic pathways terminate on principal glutamatergic neurons and local inhibitory GABAergic interneurons. Activation of these pathways ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 34 (August 24, 2021), pp. 1-9 (9 pages) Dendrites play an essential role in the integration of highly ...

The brain’s rules seem simple: Fire together, wire together. When groups of neurons activate, they become interconnected. This networking is how we learn, reason, form memories, and adapt to our world ...

Shedding light on how the brain fine-tunes its wiring during learning, a new study finds that different dendritic segments of a single neuron follow distinct rules. The findings challenge the idea ...

Breakthroughs, discoveries, and DIY tips sent every weekday. Terms of Service and Privacy Policy. One of the brain’s most important properties is its flexibility ...