Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, ...

Ever since she first experienced such hallmark COVID-19 symptoms as fever, shortness of breath, and muscle pain, in March 2020, 39-year-old Miriam has continued to suffer. In 2021, her health ...

Machine-learning analysis identifies factors predicting T cell collection efficiency in CAR T-cell therapy for DLBCL patients. Higher blood volume, not higher circulating T-cell numbers, correlates ...

Bendamustine treatment before apheresis is known to reduce survival in large B-cell lymphoma (LBCL) patients receiving chimeric antigen receptor (CAR) T-cell therapy. Bendamustine has been shown to ...

Canakinumab Versus Placebo in Combination With First-Line Pembrolizumab Plus Chemotherapy for Advanced Non–Small-Cell Lung Cancer: Results From the CANOPY-1 Trial The study included CAR T-cell ...

Study suggests CD4+ T cells mediate these immune-related toxicities ...

When Michael Linenberger, MD, retires from Fred Hutchinson Cancer Center at the end of 2022, his legacy will be felt by coworkers, trainees, patients and their families long after he has left the ...

An acute reduction in total cholesterol of ≥65%, or in LDL cholesterol of ≥70%, during each procedure; An interval mean total cholesterol of <7 mmol/l or LDL cholesterol <6.5 mmol/l (or decreases of ...

There is limited information on the pharmacotherapeutic management of children with homozygous FH from birth onwards, especially with regards to the initiation of drug treatment. However, clinicians ...