Angiotensin-converting enzyme (ACE) expression by myeloid cells is increased in response to infection. Forced ACE overexpression in mouse macrophages increases their ability to respond to infection ...

In this study, we used the linked electronic health care records of 5.6 million persons in the United Kingdom from the Clinical Practice Research Datalink (CPRD) 4 to investigate the incidence of ...

Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Losartan may help stop the epileptic process in certain patients with hypertension. An observational study that analyzed medical records of 2.26 million patients with hypertension found a roughly 30% ...

Atrial fibrillation, or AFib, is the most common heart rhythm disorder. With AFib, the beating of the upper chambers of your heart (the atria) becomes irregular, and blood has a harder time reaching ...

Blood pressure medicines are among the most commonly prescribed drugs in the world. Millions of people take them every day to ...

In this rapidly evolving setting, clinicians are weighing the alleged harm of continuing these medications in patients for whom ACE inhibitors and ARBs have known benefit against the harm to their ...

Angiotensin II, the principal effector peptide of the renin-angiotensin-aldosterone system (RAAS), has potent vasoconstrictive and other effects that can lead to cardiac and renal complications.