Solving the structure of an amyloid protein gives new insight into limb-girdle muscular dystrophy type 3 (LGMD D3) and functional protein aggregation. LGMD D3 is a rare disease characterized by slow ...

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly ...

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein. A member of the RNA-associated ...

Transthyretin amyloidosis (ATTR) is a rare, progressive and highly aggressive degenerative disease. It is caused by the ...

For decades, the structures of repetitive, flexible folds of amyloid fibrils eluded X-ray crystallographers, but with the advent of cryo-electron microscopy, these elusive amyloids were no longer able ...

Though there is so much to learn about the way Alzheimer's develops in the human brain, amyloid beta proteins have long been implicated in its advance. A new study has uncovered a previously unknown ...

What do neurodegenerative diseases and suntans have in common? Scientists at the Scripps Research Institute have found an intriguing molecular connection. In neurodegenerative disorders such as ...

Lauren E. Buchanan, Joshua K. Carra, Aaron M. Fluitt, Andrew J. Hoganson, Sean D. Moran, Juan J. de Pablo, James L. Skinner, Martin T. Zanni Proceedings of the ...